Working in collaboration with the University of Kentucky Center for Transplant and Organ Failure and the Gill Heart Institute, the Campbell lab manages a collection of cardiac tissue isolated from organ donors and patients undergoing surgeries.
Since 2008, we have procured ~5000 samples from different regions of ~250 human hearts. Most of the samples are flash-frozen and subsequently stored in the vapor phase of liquid nitrogen but we have also performed experiments using living myocytes and electrically isolated trabecualae. All of the samples are linked to medical records.
The program has received financial support from the University of Kentucky Center for Muscle Biology, the University of Kentucky Center for Clinical and Translational Science, and the American Heart Association (Grant-in-Aid). The PIs of the program have been Mark Bonnell, MD (Surgery, 2008-2010), Chuck Hoopes, MD (Surgery, 2010 to 2014), Maya Guglin, MD (Cardiology, 2014 to present).
When possible, the Campbell lab wants to use these valuable samples to help support collaborations with other research labs. However, we want to do this without draining our limited resources and/or detracting from research programs at the University of Kentucky. This page describes some general (non-binding) guidelines that will help us to achieve these goals.
If you have questions, please email email@example.com.
Our IRB protocol allows us to share samples acquire after November 2013 with collaborators at other institutions. This accelerates research that will help patients by allowing scientists at other institutions to perform experiments that we would not be able to complete by ourselves.
Before we can distribute samples to a new investigator, we need
If you would like to collaborate with us, please email firstname.lastname@example.org.
Our IRB allows us to share deidentified medical data relating to the patients and/or organ donors. This is extracted from the medical records (in the case of patients) and UNOS records (in the case of organ donors). We do not have complete data about every sample.
Collaborators are expected to pay for shipping and handling and any other reasonable costs associated with sample preparation.
Collaborators who wish to acquire samples on an ongoing basis are expected to build relevant costs into their grant applications. This will help the Campbell lab to maintain and build the resource.
Please email email@example.com to discuss options and to arrange for supporting documentation.
The Campbell lab recommends the following procedures for authorship.
Cardiac samples >