We use mathematical models of contracting muscle to help us interpret our experimental data and to guide future work. The modeling helps us to understand how different molecular-level effects impact muscle contraction. We want to use this information to help us identify key interventions that can help improve muscle function in patients with different forms of disease.
You can read more about this work by clicking on the links below.
Software for modeling muscle contraction
Spatially explicit modeling of half-sarcomeres
Other groups working in this area
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